In a trial indexed in the NLM’s PubMed database (PMC13203555) in May 2026, Antioxidants (a scientific journal from the Multidisciplinary Digital Publishing Institute based in Switzerland) published a study of 42 healthy adults who ate a measured amount of tomato paste daily for three months. At the end of the study, the participants gained 7.2 points on standardized cognitive tests in measurements of concentration. The authors determined that, “neural changes suggest that tomato intake, specifically lycopene, promotes functional reorganization of large-scale brain networks, enhancing neural efficiency and adaptability through the pruning of redundant cross-network interactions.”

Wide news coverage followed the publication of these finding, as it was “the first clinical trial to link changes in the antioxidant lycopene with alterations in functional brain connectivity.” These findings are promising and suggest that the lycopene in tomato paste is beneficial to all, though the study results are limited, as it only examined the effects on healthy participants.
Evidence of the benefit of tomato juice on those with a traumatic brain injury came recently from elsewhere. A 2026 Scientific Reports trial of 67 traumatic brain injury patients found that those given 300mL (1.25 cups) of tomato juice daily for 14 days had a lower C-reactive protein level, a higher Glasgow Coma Scale score and a shortened intensive care unit stay. Clinical investigations have also confirmed that lycopene reduces inflammatory markers and improves gastrointestinal and neurological functions in patients with TBI.
Incorporating tomato paste and tomato juice into your diet is quite easy, and tasty. For example, thick uncooked tomato paste can be a base for bruschetta. Tomato juice is the base of a (Virgin) Bloody Mary. Additionally, a 2005 NLM-indexed study titled Increases in plasma lycopene concentration after consumption of tomatoes cooked with olive oil shows that tomato products retain lycopene after cooking, so simply adding tomato paste into sauce is beneficial.










