What the Reclassification of Marijuana Means for the Brain Injured

“Justice Department Places FDA-Approved Marijuana Products and Products Containing Marijuana Subject to a Qualifying State-issued License in Schedule III, Strengthening Medical Research While Maintaining Strict Federal Controls.” This headline, which appeared on the Department of Justice’s official website on April 23, 2026, refers to the Executive Order signed by President Trump.

Advocates and politicians have pushed for this change for years, arguing cannabis carries undeniable medical value. As of April 2026, medical marijuana use is legal in 40 states. Following many years of federal research that confirmed the potential benefits of marijuana use for medical conditions, this Executive Order reclassifies state-licensed medical marijuana from Schedule I, the most restrictive federal drug category, to the less regulated Schedule III. Acting Attorney General Todd Blanche stated the decision, “allows for research on the safety and efficacy of this substance, ultimately providing patients with better care and doctors with more reliable information.”

For brain injury survivors, the implications may be significant. One study, available on PubMed, found that patients with acquired brain injury have reported improvements in mood, anxiety, headache, sleep, and quality of life through medical cannabis use. Government-funded research also indicates that the non-psychoactive cannabis compound CBD, and THC, the primary psychoactive compound in cannabis that is responsible for the “high”, may be effective for pain management, anxiety, and insomnia, all of which are common symptoms following brain injury. (These benefits are debatable. Another major analysis found that medicinal cannabis does not effectively treat anxiety, depression, or PTSD, and may even worsen mental health in some cases.)

As always, caution is warranted. The CDC has proven that cannabis use affects brain development. Beyond brain development, a 2024 CDC report states, “cannabis use directly affects brain function — specifically the parts of the brain responsible for memory, learning, attention, decision-making, coordination, emotions, and reaction time.” Chronic marijuana consumption may reduce dopamine responsivity, increase negative emotionality, and induce anhedonia, meaning a reduced ability to experience pleasure or a loss of interest in previously enjoyed activities. These possible negative consequences are a significant concern for survivors, who already have cognitive issues and may struggle with low motivation.

While this rescheduling opens the door to better science, always consult a physician before using cannabis.

Family Trauma Means Mullin’s Mission Goes Beyond Political Party

As President Trump’s nominee to lead the Department of Homeland Security, Senator Markwayne Mullin (OK) has been subject to an extremely contentious confirmation. However, previously, Mullin has worked with both Republicans and Democrats. Specific to this site, he has worked across party lines to pass bills that are very important and extremely dear to him, related to traumatic brain injury. Therefore, as a TBI survivor myself, I find it important to look back at his record, related to the topic:

In January 2020, Sen. Markwayne Mullin’s 15-year-old son was subject to a severe traumatic brain injury during a wrestling match. (Apparently, during his son’s most trying time, President Trump called almost daily and offered his personal plane. The President also later visited his son at the rehab center.) Rehabilitation, which professionals estimated would take years, was completed within 9 months and Mullin’s son is now in college.

Since the unfortunate incident, Senator Mullin has channeled his anguish and frustration into finding answers. His legislations related to TBI tend to focus on research funding and diagnostic standardization for brain injury. Only six months ago, the Senator earnestly reaffirmed his devotion to the issue when he stated, “That is why we must continue to bring awareness to this critical injury. I am honored to join my colleagues on this resolution to recognize Friday, September 19th, as National Concussion Awareness Day.”

Concrete examples of his bipartisan push forward for the brain injured community include S. 4755, Traumatic Brain Injury Program Reauthorization Act of 2024, co-led with Senator Bob Casey (D). When that bill expired, Mullin reintroduced it as the TBI Program Reauthorization Act of 2025, S. 2898, on September 23, 2025, with co-sponsors Senators Andy Kim (D), John Cornyn (R), Alex Padilla (D), and Catherine Cortez Masto (D).  (The 2025 version expanded coverage to include all acquired brain injuries.)

(Devotion to issues that relate to brain injury do not represent the entirety of legislation introduced by Senator Mullin while he has been in the Senate. Additionally, this article is not a comment on Senator Mullin’s nomination to head the DHS.)