Teletherapy Promising for TBI Emotional Recovery

A major government-funded initiative is further advancing the understanding of teletherapy for emotional health challenges following traumatic brain injury. In December 2025, the U.S. Department of War announced a $4.3 million multi-site study testing Building Emotional Self-Awareness Teletherapy (BEST), led by the Hackensack Meridian JFK Johnson Rehabilitation Institute (NJ) and designed to help brain injury survivors recognize and regulate emotions.

The DoW’s Congressionally Directed Medical Research Programs is funding this nationwide study through its Traumatic Brain Injury and Psychological Health Research Program with partner institutions, including the Indiana University School of Medicine, the National Intrepid Center of Excellence, and the University of South Florida. The study will enroll 152 civilian and military participants experiencing emotional dysregulation after mild traumatic brain injury.

The federal government’s exploration into telehealth, in relation to brain injury, has long been studied. As early as 2003, the NIH reported that, “A case study is presented in which teletherapy was successfully utilized to improve the functional outcomes, both physical and cognitive, of a patient with a severe TBI.” More recent government-supported research, led by the University of Washington and UC San Diego and published in July 2025 in Frontiers in Neurology found that telehealth interventions significantly improved depression, anxiety, PTSD, and sleep symptoms in service members with concussions.

Preliminary results are encouraging: 83% of BEST participants reported noticeable improvement in functioning. These developments offer hope that accessible remote therapy can transform emotional recovery for millions affected by brain injury.

Military Brain Injury Research Receives $5.3 Million Federal Grant

University of Virginia School of Medicine and Naval Medical Research Command researchers received a $5.3 million Department of Defense grant announced November 21, 2025, to combat blast-related brain injuries affecting military personnel.

“This is about moving from concern to capability, turning careful science into practical ways to identify, prevent, and treat blast-related brain injury,” said Dr. James Stone, a UVA Health radiologist leading the research. The four research projects will explore the neurovascular unit—where blood vessels and brain tissue interact—and how damage to this system causes chronic health conditions.

Dr. Stone explained that many service members “do not feel like the person they were before they entered the military” due to blast exposures, noting that providing diagnosis and explanation “would be an enormous contribution to this community.”

The project builds on nearly 20 years of research and aims to develop biomarkers, establish safe exposure limits, and create treatment protocols.

“We are very optimistic that the work being done right now is going to make a real difference for these affected populations,” Stone said.

UC/DVA Brain-Gut Study Results May Bring Relief

“Colorado researchers think they might be able to help veterans with traumatic brain injury and PTSD by improving the health of their gut microbiome,” reported Colorado Public Radio on November 9, 2025.

A University of Colorado School of Medicine study, focused on veterans who experience both brain injury symptoms and severe gastrointestinal distress, has just wrapped up. As Dr. Lisa Brenner, a clinical research psychologist at the Department of Veterans Affairs and the UC School of Medicine, and the lead researcher for this study, says, “One soldier I talked to started talking to me about how in addition to his brain injury symptoms, his guts hurt for several weeks after he was exposed to a blast.”

The research team used Lactobacillus rhamnosus, a specific probiotic strain designed to reduce inflammation and calm the body’s systems. Though full results with not be available until next year, researchers emphasize their focus on scientifically validated – single-strain probiotics rather than over-the-counter multi-strain products, ensuring precise treatment effects for veterans in need.

This targeted OTC approach could decrease TBI symptoms for all brain injury survivors.

Creatine’s Brain Benefits for Wellness & Recovery

Creatine is experiencing unprecedented attention in 2025, with sales surging 120% year-over-year according to recent industry reports. This supplement, traditionally associated with muscle building, is now gaining recognition for brain health benefits backed by current research published in NIH databases, military sites, and public universities.

For everyone, creatine enhances brain energy metabolism. A 2024 NIH meta-analysis of 16 studies found supplementation improves memory, attention, and information processing speed in adults. (Dosage depends on patient’s weight and other personal aspects, so it should be calculated with the aid of a medical professional.) The brain consumes 20% of the body’s energy, and creatine helps maintain ATP levels during demanding cognitive tasks, as reported to such sources as NCBI, which is part of the NIH, and in a May 25, 2025 article in Men’s Health.

For brain-injured individuals, benefits are more pronounced. Military research from July 2025 shows creatine may improve mild TBI outcomes, According to a TIME article, published on September 2, 2025, Matthew Taylor from University of Kansas Medical Center notes the supplement shows brain-boosting potential. Even NIH-published studies from almost 20 years ago, 2006-2008, demonstrate significant improvements in pediatric traumatic brain injury recovery from creatine, including reduction of ICU stays and enhanced cognitive function.

“We’re seeing a lot of other applications for creatine now in terms of its role with certain neurodegenerative diseases, its role in brain health, and potentially both a prophylactic and treatment role for [traumatic brain injury] and concussion,” says Shawn Arent, PhD, chair of the department of exercise science at the University of South Carolina.

INFORMATION PAPER ON CREATINE AND TRAUMATIC BRAIN INJURY, Traumatic Brain Injury Center of Excellence, July 2025 – https://health.mil/Reference-Center/Publications/2025/09/25/TBICoE-Information-Paper-on-Creatine-and-TBI

Navy’s Secret Brain Injury Study

The United States Navy’s secretive Project Odin’s Eye, which studies traumatic brain injuries among elite fighter pilots, has prompted a congressional investigation into the service’s handling of aviator health risks.

House Oversight Committee Chairman James Comer (KY) and Military Affairs Subcommittee Chairman William Timmons (SC) are demanding answers about the project, which was launched without formal approval from Navy Medical and Air Commands. The initiative, originally created for Navy SEALs in 2024, quietly expanded to include TOPGUN pilots experiencing brain trauma from repeated catapult launches, high-G maneuvers, and arrested carrier landings.

Last year, Congress responded with the Blast Overpressure Safety Act, which would have required all military branches to track blast exposure and implement baseline brain scans for recruits. H.R.8025 was introduced to the House on April 16, 2024, by Rep. Ro Khanna (CA); S.4109 was presented to the Senate on April 11, 2024, by Elizabeth Warren (MA). Both bills were referred to their respective Committee of Armed Services, but no further action seems to have been taken.

On Monday, September 15, 2025, the independent news source Navy Times published information regarding that current Congressional investigation that reveals the hidden toll these forces take on naval aviators. The article quotes pilots who describe carrier landings as “controlled crashes” that subject their brains to repeated jolting trauma.

Professor Honored by Military for Groundbreaking TBI Research

Mary Jo Pugh, PhD, RN, a University of Utah epidemiology professor, recently earned national recognition with an Outstanding Research Accomplishment Award from the 2025 Military Health System Research Symposium. Reported on Monday, August 18 by the University, she is one of only two investigators nationwide to receive this honor. Pugh was celebrated for her pioneering work uncovering the long-term consequences of traumatic brain injury (TBI) in veterans.

Pugh leads critical research for the Department of Defense and VA, directing the Data and Biostatistics Core for LIMBIC-CENC, the Long-Term Impact of Military-Relevant Brain Injury Consortium – Chronic Effects of Neurotrauma Consortium (www.limbic-cenc.org/). Her work has revealed previously unknown connections between TBI and conditions like dementia, cardiovascular disease, and cancer. By integrating VA and DoD health data, Pugh’s research helps identify veterans at highest risk for complications, paving the way for preemptive interventions and improved care for those who served.

TBI & PTSD Treatment Gains Congressional Momentum

Congressional efforts to expand hyperbaric oxygen therapy (HBOT) access for veterans with traumatic brain injuries and PTSD are advancing through multiple legislative channels in 2025.

Congressman Andy Biggs (AZ) reintroduced H.R. 72, the TBI and PTSD Treatment Act, on January 3, 2025, alongside co-sponsors Representative Elijah Crane (AZ) and Representative Paul Gosar (AZ). The bill was referred to the House Veterans’ Affairs Committee and subsequently to the Subcommittee on Health on February 6, 2025.

Additionally, Congressman Greg Murphy (NC) championed H.R. 1336, the Veterans National Traumatic Brain Injury Treatment Act, which successfully passed the House Veterans’ Affairs Committee on May 6, 2025. This bipartisan legislation establishes a pilot program for HBOT treatment and garnered support from twelve co-sponsors across party lines.

Both bills target the veteran suicide epidemic, with over 17 veterans lost daily. HBOT accelerates brain healing by delivering elevated oxygen to damaged tissue, with studies showing significant PTSD symptom reduction within four weeks of treatment.

The legislation aims to remove VA bureaucratic barriers and provide veterans additional treatment options beyond traditional therapies, representing a critical step toward addressing the mental health crisis affecting America’s veterans.

New Study Reaffirms Role of IL-33 in Recovery

A groundbreaking study, published by the NIH and reported on by the Military Medical Research Journal in August 2025, has shed new light on how our brains respond to injury, focusing on a protein called IL-33 that acts as the body’s internal alarm system.

When brain cells are damaged—whether from a traumatic injury, stroke, or repeated mild impacts like those seen in contact sports—they release IL-33 as a distress signal. This protein, known as an “alarmin,” alerts the immune system that something is wrong.

The August 2025 research, conducted in both mice and humans, revealed that IL-33 plays a crucial protective role after brain injury. The study found that when IL-33 levels drop following repetitive mild brain trauma, cognitive problems—like memory loss and difficulty thinking clearly—become significantly worse.

Here’s how it works: IL-33 helps special immune cells called microglia (the brain’s cleanup crew) remove harmful debris and damaged proteins that accumulate after injury. When IL-33 is functioning properly, these cleanup cells work efficiently to clear away toxic buildup, particularly a problematic protein called amyloid-beta.

The researchers discovered that supplementing IL-33 levels through nasal administration dramatically improved brain function and cognitive recovery in injured animals. This finding offers hope for developing new treatments for people suffering from brain injuries, potentially helping millions recover more effectively from trauma-related cognitive decline.

Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis: https://pubmed.ncbi.nlm.nih.gov/40764944/

Texas First to Fund New Psychedelic Research

Texas has made history by becoming the first state to allocate significant public funding for psychedelic medicine research. Governor Greg Abbott signed Senate Bill 2308 into law in June 2025, committing $50 million to FDA-approved clinical trials of ibogaine, a psychedelic compound derived from an African shrub.

The groundbreaking legislation represents the largest government investment in psychedelic research to date, positioning Texas as a global leader in this emerging field. The initiative aims to develop FDA-approved treatments for opioid addiction, traumatic brain injury (TBI), and PTSD—conditions that have devastated countless lives across America.

Rick Perry’s Pivotal Role

Former Texas Governor Rick Perry has emerged as an unlikely but passionate advocate for ibogaine research. His involvement began through his relationship with Navy SEAL veterans Marcus and Morgan Luttrell, who found relief from combat-related trauma through ibogaine treatment in Mexico. After witnessing their remarkable recoveries, Perry dedicated himself to advancing this cause, even launching the nonprofit Americans for Ibogaine.

“I’ve spent most of my adult life in public service, and few things have moved me like what I’ve witnessed with this psychedelic drug,” Perry wrote in a recent op-ed, describing how ibogaine helped veterans overcome years of opioid dependence and psychological trauma.

Promising Results for Brain Injury

Recent Stanford Medicine research found that ibogaine, when combined with magnesium for heart protection, safely reduced PTSD symptoms by 88%, depression by 87%, and anxiety by 81% in combat veterans with traumatic brain injuries. The treatment appears to promote neuroplasticity, potentially helping the brain repair itself after injury.

While primarily focused on veterans, the research could benefit anyone suffering from brain trauma, including athletes with concussion-related injuries and accident victims. Texas’s historic investment may lead the way to finally bringing this promising treatment to American patients who have long traveled abroad seeking relief.

Texas SB 2308: https://capitol.texas.gov/BillLookup/History.aspx?LegSess=89R&Bill=SB2308

Government’s Critical Role in Toxic Exposure Crisis

Burn pits are massive open-air waste disposal sites used extensively by the military in combat zones. Specifically, from 2001 to 2011 in Iraq and Afghanistan, these giant outdoor incinerators were used to burn everything from plastics and medical waste to chemicals, batteries, ammunition, and office equipment, which resulted in the release of dangerous cocktails of carcinogens and toxic chemicals into the air that service members breathed daily. The Department of Defense estimates that 3.5 million troops were exposed to this toxic smoke during recent wars, making burn pit exposure one of the most widespread environmental hazards faced by military personnel.

While outcomes to exposure to these burn pits involving respiratory and cancer risks have previously been exposed, groundbreaking research released in July 2025 has revealed alarming long-term neurological consequences. A study of 440,000 veterans, conducted by the National Institutes of Health, Department of Defense, and Department of Veterans Affairs found that troops exposed to burn pit smoke had dramatically higher rates of brain injuries and psychological trauma. Veterans who lived near burn pits for at least 129 days were 27% more likely to experience severe stress symptoms and 37% more likely to suffer brain injuries compared to those at cleaner bases. Those with extended exposure of over 474 days showed 68% higher rates of severe stress and 124% increased likelihood of brain damage. More so, 90% of troops who died by suicide had served at bases with large burn pits for extended periods. The reason for these increases and terrible results appears to be exposure to toxic chemicals which disrupt brain function and neurotransmitters.

The military has responded with comprehensive reform measures. The Department of Defense has closed most burn pits and plans to eliminate all remaining sites. The 2022 PACT Act expanded healthcare and disability benefits for millions of veterans exposed to toxic environments, while 2025 H.R. 1, One Big Beautiful Bill Act, allocates $2 billion to defense health programs. These efforts represent crucial progress toward comprehensive care for veterans facing the invisible wounds of toxic exposure.