Grey’s Anatomy star Eric Dane was set to present an award at the Emmy Awards on September 14, 2025.  Instead, the actor missed this year’s awards entirely. After a fall in his kitchen caused a head injury that required stitches, he spent a much less glamorous evening in the hospital.

Earlier this year, Dane revealed that he suffered from amyotrophic lateral sclerosis. Reports say that Dane has largely lost control over the right side of his body due to the progressive neurodegenerative disease, illustrating how ALS-related motor control loss can lead to falls and subsequent head trauma.

The National Institute of Neurological Disorders and Stroke acknowledges head injury as a potential risk factor ALS, though researchers emphasize more investigation is needed to understand the intricate connection. An October 2025 study report found on the NLM database, and initially published on JAMA Network, states, “TBI might represent an early complication of… preclinical ALS at risk of falls or other events culminating in TBI.”

Various studies have shown that there is a complex relationship between the two conditions. Data from the National ALS Registry, published by the NIH in January 2025, found that over half of ALS patients had experienced head injuries, with multiple injuries and those occurring before age 30 showing stronger associations. The aforementioned JAMA Network study, examining the connection between TBI and ALS in over 342,000 adults, found that individuals with a history of traumatic brain injury had more than double the risk of developing ALS. (The elevated risk, though, was confined to the two years immediately following brain injury, with researchers suggesting this may indicate reverse causality—that the head injury could again be an early consequence of subclinical [undiagnosed] ALS rather than its cause.)