In June 2025, Case Western Reserve University and University of Cincinnati researchers received an Air Force Research Laboratory grant to develop nanotherapeutics for traumatic brain injuries and hemorrhages. Nanotherapy is a medical approach using nanoparticles—tiny therapeutic devices ranging from 1-100 nanometers in size, similar to biological molecules like proteins. The CWRU research team created synthetic platelets from nanoparticles called liposomes that mimic natural platelet functions to stabilize blood clots and reduce bleeding in complex injury scenarios. Nanotherapies already help cancer patients by improving drug targeting and reducing systemic toxicity while enabling sustained drug release. The government and research institutions are optimistic about this technology’s potential to transform trauma care, offering critical solutions for battlefield medicine, mass casualty events, and emergency situations where traditional blood transfusions are unavailable, ultimately bridging gaps between battlefield needs and real-world medical challenges for both military personnel and civilians.